Rhodium-Catalyzed C-H Amination. An Enabling Method for Chemical Synthesis

Du Bois, J.

Org. Proc. Res. Dev.,
2011, 758-762; 10.1021/op200046v

05/2011

The CCHF seeks to bring C–H Functionalization into the center of synthetic logic, for the construction of a broad range of molecular scaffolds. This account from the Du Bois group provides an overview of the selective methods for C–H amination from the perspective of a process group, paying special attention to the mild reaction conditions, catalyst effciciency and scalability of the reaction.

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